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GLUCONEOGENESIS

Wednesday, June 29, 2022

Is a metabolic pathway that results in the generation of glucose from certain non - carbohydrate carbon substrates. It is ubiquitous process, present in plants, animals, fungi, bacteria, and other microorganisms. 

Formation of glucose within the body specially by the liver from substances (such as fats and proteins) other than carbohydrates. Occurs primarily in liver; serves to maintain euglycemia  during fasting. Enzymes also found in kidney, intestinal epithelium.

Odd chain fatty acids yield 1 propionyl-CoA during metabolism, which can enter the TCA cycle as succinyl-CoA, undergo gluconeogenesis, and serves as a glucosa source. ( It's odd for fatty acids to make glucose). Even-chain fatty acids cannot produce new glucose, since they yield only acetyl CoA equivalents.

On other words, ODD FATTY ACIDS SERVES AS A GLUCOSE SOURCE FOR FUEL WHEN IS NECESSARY OR DURING FASTING.


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Medical and Nutrition Assessment
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